Tottenham's clash with Manchester City is the pick of the bunch from the EFL Cup fourth-round draw.

City sealed their progress from round three by beating Watford 2-1 at home on Tuesday, while Spurs overcame Coventry City last week.

The Premier League heavyweights will go head-to-head for a place in the quarter-finals, while holders Liverpool face a tough trip to in-form Brighton.

Manchester United, who were in Europa League action on Wednesday, were drawn against Leicester City. Chelsea will face the winner of AFC Wimbledon's postponed match with Newcastle United, which will take place at St James' Park next week.

Aston Villa and Crystal Palace will face off in another all-Premier League encounter, while Southampton and Brentford were drawn at home against Championship opposition in Sheffield Wednesday and Stoke City respectively.

Arsenal, 5-1 victors over Bolton Wanderers, will visit Preston North End.

Fourth-round draw in full:

Brentford v Sheffield Wednesday

Southampton v Stoke City

Tottenham v Man City

AFC Wimbledon / Newcastle United v Chelsea

Man Utd v Leicester City

Brighton v Liverpool 

Preston North End v Arsenal 

Aston Villa v Crystal Palace