Libertad defended their home turf to secure a 2-0 victory in the first leg of the CONMEBOL Copa Sudamericana Round of 16 Playoffs against Universidad Católica. The goals were scored by Óscar Cardozo and Lucas Sanabria.

With this result, the Paraguayan team heads into the away match in Ecuador with a solid lead, while Universidad Católica will look to overturn the aggregate score to advance to the next round.