The win moved Panama, playing in only its second Copa America, up to second on six points, three more than the U.S., as the central American side reached the knockout stage for the first time.

Uruguay finished with nine points.

Jose Fajardo, Eduardo Guerrero and Cesar Yanis scored for Panama with Bolivia's lone goal coming from Bruno Miranda.

Bolivia exits the tournament after three straight losses having conceded 10 goals and scoring just one.

Bolivia needed a win with only a slim chance of staying alive in the tournament, but it was Panama who broke the deadlock in the 22nd minute when Cristian Martinez set up Fajardo.

The 30 year-old forward expertly controlled Martinez's header into the box, let it bounce and volleyed the ball past Bolivia goalkeeper Guillermo Viscarra.

Bolivia equalised in the 69th minute when it cut through Panama's midfield and defence, with Ramiro Vaca finding Miranda, who slipped his shot past the keeper.

Bolivia nearly took the lead in the 78th minute when Panama goalkeeper Orlando Mosquera ventured out of the box but Miguel Terceros's long-range effort was thwarted by the retreating Panama defence.

A minute later, Panama wrested back control of qualification when Davis curled in a cross from the left and Guerrero connected with a glancing header - his first goalfor his country.

Yanis made sure of victory in the first minute of added time, blasting a right-footed shot into the top right corner after he was put through on goal, sparking wild celebrations at the Inter&Co Stadium.